Table 4

Causes of Death by Center Volume

Center Volume
≤10 (n = 195)11–30 (n = 630)31–50 (n = 603)>50 (n = 469)
Device malfunction4 (2.1)20 (3.2)18 (3.0)11 (2.3)
Hemolysis2 (1.0)3 (0.5)4 (0.7)2 (0.4)
Neurological dysfunction31 (16)97 (15)128 (21)97 (21)
Major bleed event4 (2.1)19 (3.0)18 (3.0)8 (1.7)
Infection15 (7.7)37 (5.9)30 (5.0)21 (4.5)
RV failure8 (4.1)25 (4.0)20 (3.3)8 (1.7)
MSOF27 (14)110 (18)119 (20)101 (22)
Myocardial infarction0 (0)4 (0.6)3 (0.5)2 (0.4)
End-stage heart failure12 (6.2)31 (4.9)36 (6.0)42 (9.0)
Cardiovascular: other9 (4.6)26 (4.1)19 (3.2)19 (4.1)
Arrhythmia3 (1.5)15 (2.4)13 (2.2)14 (0.7)
Sudden cardiac death5 (2.6)24 (3.8)23 (3.8)21 (4.5)
Non-CNS embolism2 (1.0)5 (0.8)1 (0.2)1 (0.2)
Pulmonary failure19 (9.7)42 (6.7)38 (6.3)29 (6.2)
Renal failure1 (0.5)2 (0.3)2 (0.3)4 (0.9)
Hepatic failure0 (0)3 (0.5)3 (0.5)2 (0.4)
GI dysfunction0 (0)8 (1.3)1 (0.2)4 (0.9)
Cancer2 (1.0)11 (1.7)4 (0.7)5 (1.1)
Psychiatric0 (0)1 (0.2)2 (0.3)2 (0.4)
Noncardiovascular, other19 (9.7)46 (7.3)29 (4.8)27 (5.8)
Trauma/accident3 (1.5)5 (0.8)3 (0.2)2 (0.4)
Withdrawal care29 (15)96 (15)89 (15)47 (10)

Values are n (%). Overall p value >0.05.

CNS = central nervous system; GI = gastrointestinal; MSOF = multisystem organ failure; RV = right ventricle.