Table 1

Baseline Characteristics

All
(n = 62)
Ages 20–39 Yrs
(n = 20)
Ages 40–59 Yrs
(n = 22)
Ages 60–80 Yrs
(n = 20)
Age (yrs)49 (45–54)29 (27–33)49 (47–52)69 (66–71)
Female/male32/3010/1012/1010/10
Weight (kg)75 (72–78)72 (67–78)77 (72–82)75 (70–80)
BMI (kg/m2)24 (24–25)23 (21–24)25 (24–27)25 (24–26)
BSA (m2)1.9 (1.9–1.9)1.9 (1.8–2.0)1.9 (1.8–2.0)1.9 (1.8–2.0)
Hemoglobin (mmol/l)8.9 (8.7–9.1)8.8 (8.4–9.2)9.0 (8.7–9.3)8.8 (8.4–9.2)
eGFR (ml/min/1.73 m2)79 (76–83)88 (83–93)74 (67–81)77 (72–82)
HbA1c (mmol/mol)35 (34–35)33 (32–34)34 (33–36)36 (35–38)
CRP (mg/l)1.9 (1.4–2.5)1.9 (1.1–2.7)1.9 (1.2–2.6)2.1 (0.6–3.5)
TSH (103 × IU/l)1.8 (1.6–2.0)2.0 (1.6–2.4)1.8 (1.5–2.1)1.6 (1.2–2.1)
NT-proBNP (pmol/l)11 (8–14)7 (6–8)10 (7–13)16 (7–24)
FEV1 (l)3.4 (3.2–3.6)3.9 (3.5–4.3)3.4 (3.1–3.7)3.0 (2.7–3.4)
FVC (l)4.5 (4.2–4.7)4.9 (4.3–5.5)4.5 (4.1–4.9)4.0 (3.5–4.5)
VO2-max (l/min)2.6 (2.4–2.8)3.0 (2.6–3.3)2.7 (2.4–3.0)2.2 (1.9–2.5)
VO2-max/weight (ml/min/kg)35 (33–37)41 (38–45)34 (31–37)29 (26–32)
HR (beats/min)63 (61–66)63 (57–69)64 (60–69)62 (58–66)
SBP (mm Hg)132 (128–136)119 (115–124)133 (126–140)143 (136–151)
DBP (mm Hg)75 (72–78)65 (61–70)81 (78–85)77 (72–82)
MAP (mm Hg)89 (86–91)79 (75–82)94 (90–98)92 (88–97)
LV mass index (g/m2)78 (73–83)75 (65–84)81 (71–92)77 (68–86)
LVEDV (ml)98 (91–105)107 (90–123)94 (84–105)93 (83–104)
LVESV (ml)37 (34–41)42 (34–50)38 (32–43)33 (28–37)
LVEF (%)62 (60–63)61 (58–63)60 (58–63)64 (61–67)
LA volume (ml/m2)24 (22–26)24 (22–27)23 (19–26)26 (22–30)
E/A1.3 (1.2–1.4)1.8 (1.6–2.1)1.2 (1.2–1.3)1.0 (0.9–1.1)
E/e′8.3 (7.5–9.0)7.1 (5.0–9.1)8.3 (7.3–9.3)9.2 (8.2–10.2)

All values are mean ± 95% Confidence intervals (CI) or n. Differences in age and LV mass index not tested.

BMI = body mass index; BSA = body surface area; CRP = C-reactive protein; DBP = diastolic blood pressure; eGFR = estimated glomerular filtration rate; FEV1 = forced expiratory volume in 1 second; FVC = forced vital capacity; HR = heart rate; LA = left atrial; LV = left ventricular; LVEDV = left ventricular end-diastolic volume; LVESV = left ventricular end-systolic volume; MAP = mean arterial pressure; NT-proBNP = N-terminal pro B-type natriuretic peptide; SBP = systolic blood pressure; TSH = thyroid-stimulating hormone; VO2-max = maximal oxygen consumption.

  • p < 0.05, for difference across age categories.