Table 3

Comparison of Characteristics of Hypervascularity Versus Normal Mucosa in Subjects With CF LVAD

Normal Mucosa
(n = 13)
Hypervascularity
(n = 22)
p Value
Age (yrs)55 (42–65)58 (44–71)0.412
Female (%)3 (23)3 (14)0.474
Ischemic etiology (%)3 (23)9 (41)0.283
Diabetes (%)5 (38)10 (45)0.686
Hypertension (%)4 (31)13 (59)0.105
CKD 4/5 (%)1 (8)0 (0)0.187
LVEF (%)20 (15–30)20 (12–25)0.894
LVEDD (cm)6.7 (5.5–7.3)5.5 (4.9–6.1)0.108
Type of LVAD0.133
 HeartMate II13 (100)17 (77)
 HVAD05 (23)
Mean duration of LVAD support (days)3273510.802
Aortic valve opening0.750.680.824
HeartMate II PI5.75.80.863
Doppler blood pressure (mm Hg)92 (84–102)85 (78–90)0.083
HeartMate II speed (rpm)9,000 (8,800–9,200)9,000 (8,800–9,200)0.809
LVAD flow (l/m)4.9 (4.3–5.3)4.4 (4.0–5.2)0.439
All gastrointestinal bleeding (%)0 (0)7 (32)0.023
AVM gastrointestinal bleeding (%)0 (0)5 (23)0.063

Values are mean (range), n (%), or %.

AVM = arteriovenous malformation; LVEDD = left ventricular end-diastolic diameter; PI = pulse index; other abbreviations as in Table 2.

  • Aortic valve opening, scored over a 10-beat average as follows: 0 = no opening; 1 = intermittent; and 2 = closed.