Table 5

Unadjusted Cumulative Incidence and Adjusted Hazards of Stroke Readmission in Patients With Pre-Existing or New-Onset Atrial Fibrillation and Heart Failure With Either Preserved or Reduced EF

Pre-Existing Atrial FibrillationNew-Onset Atrial Fibrillation
Cumulative IncidenceAdjusted RiskCumulative IncidenceAdjusted Risk
Reduced EF
(n = 3,410)
Preserved EF
(n = 6,099)
p ValueHR (99% CI)p ValueReduced EF
(n = 697)
Preserved EF
(n = 1,329)
p ValueHR (99% CI)p Value
1 yr15 (2.2)48 (3.7)0.080.91 (0.63–1.30)0.4886 (2.6)202 (3.4)0.030.67 (0.32–1.37)0.15
3 yrs23 (3.7)89 (8.2)0.0020.87 (0.66–1.16)0.22142 (5.0)339 (6.5)0.0050.56 (0.32–0.98)0.008

Values are presented as number of events (cumulative incidence per 100 patients). Rates of oral anticoagulation were 53% for heart failure with preserved ejection fraction and 57% for heart failure with reduced ejection fraction.

EF = ejection fraction; other abbreviations as in Table 4.