Table 4

Associations Between Pre-Existing or New-Onset Atrial Fibrillation and Mortality and Readmission After Adjustment for Baseline Characteristics

OutcomePre-existing Atrial FibrillationNew-Onset Atrial Fibrillation
Adjusted HR
(99% CI)
p ValueAdjusted HR
(99% CI)
p Value
Outcomes at 1 yr
 Mortality1.15 (1.08–1.22)<0.0011.12 (1.01–1.24)0.005
 All-cause readmission1.08 (1.03–1.13)<0.0011.05 (0.96–1.16)0.15
 Heart failure readmission1.13 (1.06–1.21)<0.0011.08 (0.95–1.23)0.11
 Stroke readmission1.17 (0.95–1.44)0.051.19 (0.84–1.68)0.19
 Other cardiovascular readmission0.89 (0.81–0.98)0.0020.92 (0.79–1.07)0.15
Outcomes at 3 yrs
 Mortality1.14 (1.08–1.20)<0.0011.08 (0.98–1.18)0.05
 All-cause readmission1.09 (1.05–1.14)<0.0011.06 (0.97–1.15)0.08
 Heart failure readmission1.15 (1.08–1.21)<0.0011.07 (0.95–1.20)0.16
 Stroke readmission1.20 (1.01–1.41)0.0051.27 (0.98–1.64)0.02
 Other cardiovascular readmission0.91 (0.85–0.99)0.0030.92 (0.81–1.05)0.09

The reference group was the cohort of patients with no atrial fibrillation. The multivariable models adjusted for all variables listed in Table 1.

CI = confidence interval; HR = hazard ratio.