Table 3

Univariate Cox Proportional Hazards Models for GIB Risk

HR95% CIp Value
Age (per 1-yr increase)1.019(0.999–1.040)0.06
Male (vs. female)0.949(0.556–1.621)0.85
Ischemic CMP (vs. no)1.019(0.656–1.581)0.93
History of smoking (vs. no)1.543(0.976–2.439)0.06
History of COPD (vs. no)1.525(0.902–2.579)0.12
History of GIB (vs. no)1.606(0.648–3.975)0.31
BTT strategy (vs. no)0.558(0.359–0.867)0.009
PDE5 inhibitor (vs. no)0.983(0.627–1.542)0.94
Aspirin 325 mg (vs. 81 mg)1.013(0.646–1.587)0.96
Bosentan (vs. no)0.883(0.493–1.581)0.67
Persistent AV closure (vs. no)1.199(0.740–1.943)0.46
PI - per 1 unit increase0.895(0.657–1.219)0.48
TV surgery (vs. no)1.581(0.722–3.460)0.25
TAPSE, per cm increase0.592(0.337–1.040)0.07
RAP (above vs. below median)1.712(1.047–2.798)0.03
RVEDD, per cm increase1.172(0.889–1.547)0.26

Values are n or median ± SD.

AV = aortic valve; BTT = bridge to transplant; CI = confidence interval; HR = hazard ratio; PI = pulsatility index; TV = tricuspid valve; other abbreviations as in Tables 1 and 2.

  • See Online Table 1 in the Online Appendix for details on assessment methods.

  • As measured on pre−ventricular assist device transthoracic echocardiogram.