Table 1

Patient Characteristics

Control
(n = 175)
Severe RV Dysfunction
(n = 37)
p Value
Baseline characteristics
 Age, yrs57.2 ± 11.755.3 ± 12.20.38
 Male135 (77.1)32 (86.5)0.27
 Race0.39
 Black39 (35.8)11 (29.7)
 White136 (64.2)26 (70.3)
 Other0 (0)0 (0)
 BMI, kg/m228.4 ± 5.830.0 ± 5.80.13
 History of GIB9 (4.2)1 (2.7)1.00
 Ischemic CMP81 (46.3)17 (45.9)1.00
 A fib73 (41.7)13 (35.1)0.58
 COPD27 (15.4)6 (16.2)1.00
 History of smoking95 (54.3)26 (70.3)0.10
 Type of LVAD0.43
 Heartmate II150 (85.7)34 (91.9)
 HVAD25 (14.3)3 (8.1)
 INTERMACS profile2 (2, 2)2 (1, 2)0.22
 DT strategy57 (32.6)9 (24.3)0.12
Medications
 Aspirin0.10
 0 mg5 (2.8)1 (2.7)
 81 mg85 (48.6)24 (64.9)
 325 mg85 (48.6)12 (32.4)
 PDE5 inhibitor65 (37.1)16 (43.2)0.58
 Bosentan19 (10.9)11 (29.7)0.01
Laboratory data
 Creatinine1.14 ± 0.631.21 ± 0.570.49
 INR2.22 ± 0.562.24 ± 0.620.85
 Platelets317 ± 124356 ± 1180.09
 Bilirubin1.0 (0.6, 1.6)1.2 (0.6, 2.5)0.32

Values are n (%), mean ± SD, or median (25th percentile, 75th percentile).

A fib = atrial fibrillation; BMI = body mass index; CMP = cardiomyopathy; COPD = chronic obstructive pulmonary disease; DT = destination therapy; GIB = gastrointestinal bleed; INR = international normalized ratio; LVAD = left ventricular assist device; PDE5 = phosphodiesterase 5; RV = right ventricular.

  • On discharge from index hospitalization for implantation of LVAD.