Table 1

Baseline Characteristics in the Overall Population Stratified by Ejection Fraction

LevelOverall
(N = 99,825)
Reduced Ejection Fraction (n = 48,950)Borderline Ejection Fraction
(n = 12,819)
Preserved Ejection Fraction
(n = 38,056)
p Value
N%n%n%n%
Demographics
 Age,yrsMedian99,82575.0048,95072.0012,81977.0038,05678.00<0.0001
25th63.0060.0066.0068.00
75th84.0081.0084.0086.00
Mean72.6369.6374.4475.87
± SD14.2414.7113.3113.06
Minimum18.0018.0019.0018.00
Maximum109.00109.00106.00108.00
 SexFemale49,06649.1518,02336.82626248.8524,78165.12<0.0001
Male50,75950.8530,92763.18655751.1513,27534.88
 RaceOther (includes unknown)3,2943.311,6573.404103.211,2273.24<0.0001
Hispanic (any race)7,6767.724,0908.391,0218.002,5656.76
Black19,08719.201,157123.74187314.685,64314.88
White69,37569.7731,42664.479,45874.1128,49175.12
 Insurance statusNo insurance/not documented37263.9525165.483993.278112.24<0.0001
Medicare54,03557.3325,04754.587,17458.7621,81460.35
Medicaid9,93610.545,31411.581,0978.983,5259.75
Other26,54928.1713,01228.363,54028.999,99727.66
Medical history
 AnemiaYes23,82723.879,26518.933,46427.0211,09829.16<0.0001
 SmokingYes16,09116.179,88320.261,80214.114,40611.61<0.0001
 Atrial fibrillationYes38,26638.3316,72934.185,35341.7616,18442.53<0.0001
 Atrial flutterYes3,0083.011,4993.064283.341,0812.840.012
 Coronary diseaseYes54,72654.8228,56758.367,67759.8918,48248.57<0.0001
 COPD or asthmaYes35,42435.4915,59331.854,67036.4315,16139.84<0.0001
 CVA/TIAYes16,47916.517,75915.852,19217.106,52817.15<0.0001
 DepressionYes12,53812.565,34610.921,64912.865,54314.57<0.0001
 DiabetesYes46,82146.9021,76344.466,43050.1618,62848.95<0.0001
 Previous MIYes24,57524.6214,97230.593,26425.466,33916.66<0.0001
 Peripheral vascular diseaseYes14,30614.336,85214.002,03115.845,42314.25<0.0001
 Prior heart failureYes99,825100.0048,950100.0012,819100.0038,056100.00
 HyperlipidemiaYes52,11952.2125,95453.026,92554.0219,24050.56<0.0001
 HypertensionYes80,55880.7038,06277.7610,53582.1831,96183.98<0.0001
 Renal insufficiency (creatinine >2 mg/dl)Yes23,90523.9511,28623.063,30525.789,31424.47<0.0001
 DialysisYes4,1444.151,6203.316895.371,8354.82<0.0001
 Ischemic historyYes61,59661.7032,43266.268,59667.0620,56854.05<0.0001
Cause
 IschemiaYes63,58963.7033,43868.318,83968.9521,31256.00<0.0001
 Nonischemic alcoholYes1,9374.371,4767.721582.963031.53<0.0001
 Other nonischemic causeYes9,99022.554,08221.341,22522.914,68323.62<0.0001

COPD = chronic obstructive pulmonary disease; CVA = cerebrovascular accident; MI = myocardial infarction; TIA = transient ischemic attack.