Table 3

TTR Amyloid Deposition Is Associated With More Severe Fibrosis and Lower Heart Weight After Adjustment for Age and Presence of HFpEF

Regression CoefficientSEp Value
Fibrosis, WFDM, %
 Age at death, per 10 yrs0.50.30.09
 HFpEF, vs. control2.10.4<0.001
 wtTTR present, vs. absent2.00.70.005
Expected heart weight, %
 HFpEF, vs. control32.22.5<0.001
 wtTTR present, vs. absent−8.24.00.04

The change in percentage of fibrosis or heart weight (regression coefficient and SE) associated with each covariate and significance of the association adjusting for the other covariates in the model are shown.

LV = left ventricular; SE = standard error; other abbreviations as in Tables 1 and 2.