Table 1

Baseline Subject Characteristics

Patients With HF
(n = 26)
Control Group
(n = 15)
Age, yrs51 ± 945 ± 10
Sex (male:female)16:108:7
Race (white:other)19:714:1
Body mass index, kg/m228.1 ± 4.326.6 ± 4.0
Smoking history177
Hypertension155
Diabetes61
Heart failure etiology
 Ischemic9
 Nonischemic14
 Chagasic3
NYHA functional class
 I–II22
 III4
LVEF, %30.3 ± 6.0
Systolic blood pressure, mm Hg111.6 ± 22.9127.1 ± 13.3
Diastolic blood pressure, mm Hg58.4 ± 16.069.5 ± 11.4
Creatinine, mg/dl1.25 ± 0.31.08 ± 0.1
Drugs
 Beta-blocker262
 ACE inhibitors/ARB261
 Loop diuretic230
 Aldosterone receptor antagonist120
 Hydralazine (+ nitrate)50

Values are mean ± SD or n unless otherwise noted.

ACE = angiotensin-converting enzyme; ARB = angiotensin receptor blocker; LVEF = left ventricular ejection fraction; NYHA = New York Heart Association.

  • p < 0.05 for patients with heart failure (HF) versus control subjects.