Table 4

Efficacy Outcomes According to Protocol Group

OutcomeLow-Dose
(n = 13)
Standard-Dose
(n = 22)
High-Dose
(n = 9)
Mega-Dose
(n = 51)
p Value
Urine output, ml1,125825–1,6001,4021,003–1,7951,1501,040–1,39895500–1,180<0.01
Clinic weight loss, kg0.90.8–2.51.30.9–1.81.10.9–1.30.90.4–1.20.01
Home weight loss, kg1.10.7–1.81.40.6–2.41.30.4–1.70.90–1.80.37

Values are median (interquartile range).

IQR = interquartile range.

  • p value for comparison across protocol groups.

  • p < 0.05 for comparisons between mega- and standard-dose groups and mega- and high-dose groups.

  • p < 0.05 for comparison between mega- and standard-dose groups.