Table 3

Risk of HFrEF, by LVH and Initial Biomarker Level

LVH by EchocardiographyTertile of NT-proBNPHazard Ratios (95% CI)
UnadjustedRisk-Factor Adjusted
None11.001.00
21.03 (0.64–1.65)1.00 (0.62–1.62)
31.74 (1.11–2.21)1.66 (1.05–2.62)
Yes11.03 (0.64–1.65)0.93 (0.28–3.04)
23.49 (1.72–70.6)2.92 (1.42–5.99)
36.48 (3.82–10.97)5.06 (2.89–8.86)
LVH by EchocardiographyTertile of hs-cTnTUnadjustedRisk-Factor Adjusted
None11.001.00
22.30 (1.42–3.73)1.77 (1.08–2.89)
33.64 (2.29–5.80)2.62 (1.62–4.21)
Yes12.70 (1.12–6.51)2.19 (0.90–5.32)
23.38 (1.40–8.14)2.65 (1.10–6.46)
312.94 (7.5–22.23)7.83 (4.43–13.83)

Interaction of LVH with NT-proBNP tertiles (p = 0.07) and hs-cTnT tertiles (p = 0.4).

HFrEF = heart failure with reduced ejection fraction; other abbreviations as in Tables 1 and 2.

  • Risk-factor adjusted: Adjustment covariates same as for Table 2.