Table 3

Multivariable Analysis: Individual Predictors of MACE in All Women at Delivery

FactorOR (95% CI)
Cardiomyopathy90.25 (80.61–101.05)
Valvular disease10.31 (9.50–11.16)
Multiple gestation1.49 (1.36–1.63)
Postpartum hemorrhage2.23 (2.08–2.40)
Transient hypertension1.31 (1.20–1.42)
Pre-eclampsia status
 Eclampsia vs. normal9.14 (7.50–11.13)
 Severe pre-eclampsia vs. normal2.59 (2.38–2.82)
 Mild pre-eclampsia vs. normal1.53 (1.40–1.68)
 Pre-eclampsia or eclampsia with pre-existing HTN vs. normal2.88 (2.56–3.25)
Diabetes mellitus1.60 (1.42–1.80)
Teaching hospital1.32 (1.28–1.38)
Age1.10 (1.08–1.11)
Cesarean delivery1.74 (1.68–1.81)
Race
 Asian vs. white0.72 (0.66–0.78)
 Black vs. white1.16 (1.1–1.22)
 Hispanic vs. white0.69 (0.66–0.73)
 Other vs. white0.80 (0.74–0.87)

CI = confidence interval; HTN = hypertension; MACE = major adverse cardiac events; OR = odds ratio.

  • Each factor is based on the final optimal multivariable logistic regression model in which all factors had a p value <0.1 in the univariate model were taken into account. Factors such as age, race, insurance, diabetes mellitus, valvular disease, teaching hospital, transient hypertension, pre-eclampsia status, multiple gestation, postpartum hemorrhage, cesarean delivery, year, and CDM were significantly associated with MACE after adjusting for these factors (all p values < 0.0001).