Table 1

Baseline Characteristics of STICH Hypothesis 1 Patients by Mortality Status

CharacteristicsPatients Survived
(n = 750)
Patients Died
(n = 462)
p Value
Sudden Deaths
(n = 173)
Pump Failure Deaths
(n = 82)
All-Cause Deaths
(n = 462)
Age, yrs59 (53–66)59 (53–67)61 (56–69)62 (54–69)<0.001
White race666478720.017
Previous stroke6910100.008
Renal insufficiency591712<0.001
Atrial fibrillation101516170.001
Current NYHA HF class
 I/II13/539/529/4610/49
 III/IV32/235/540/537/50.003
Creatinine, mg/dl1.1 (0.9–1.2)1.1 (1.0–1.3)1.2 (1.0–1.4)1.1 (1.0–1.4)<0.001
BUN, mg/dl22 (16–35)24 (16–37)25 (19–43)24 (17–39)0.004
LVEF, %28 (23–34)25 (20–31)24 (20–30)25 (20–32)<0.001
ESVI, ml/m275 (57–97)86 (67–111)96 (70–128)86 (65–118)<0.001
EDVI, ml/m2108 (86–132)120 (97–144)127 (102–169)120 (97–154)<0.001
Mitral regurgitation
 Mild or less85816576
 Moderate/severe15193524<0.001
Duke CAD Index (1−100)52 (39–77)65 (39–77)65 (39–77)65 (39–77)0.018
Beta-blocker878879830.046
Amiodarone81312130.005
Diuretic (loop/thiazide)61697772<0.001
Diuretic (loop/thiazide or potassium sparing)71788882<0.001
Previous ICD21220.983

Values are median (interquartile range) or %.

BUN = blood urea nitrogen; CAD = coronary artery disease; EDVI = end-diastolic volume index; ESVI = end-systolic volume index; HF = heart failure; ICD = implantable cardioverter-defibrillator; LVEF = left ventricular ejection fraction; NYHA = New York Heart Association functional class; STICH = Surgical Treatment for Ischemic Heart Failure.

  • All-cause deaths include sudden deaths, pump failure deaths, and deaths from other causes.

  • p Values are based on comparisons between patients who survived (n = 750) and patients who died (n = 462).