Table 2

Basic Demographics and Characteristics of Right Heart Catheter Substudy Participants

Placebo
(n = 10)
Urocortin-2
(n = 10)
p Value
Age, yrs63 ± 1461 ± 130.75
Male7100.21
Ethnicity1.0
 Caucasian99
 Non-Caucasian11
BMI, kg/m226 ± 527 ± 40.82
LVEF, %41 ± 1935 ± 190.46
Etiology1.0
 Ischemic40%30%
 Nonischemic60%70%
History
 CAD50%30%0.65
 Prior MI33%20%0.63
 Prior PCI0%20%0.47
 Prior CABG20%10%1.0
 Hypertension60%50%1.0
 Atrial fibrillation30%50%0.65
 Diabetes mellitus30%30%1.0
 Hyperlipidemia20%40%0.30
 CVA10%10%1.0
 Smoking70%70%1.0
 COPD20%30%1.0
Furosemide prior 24 h, mg270 ± 51814 ± 380.14
Baseline drug use
 ACEI/ARB50%30%0.65
 BB30%40%1.0
 MRA10%30%1.0
Presentation to start of infusion, h27 ± 824 ± 80.47
Baseline measurements
 Systolic BP, mm Hg133 ± 30118 ± 180.19
 Heart rate, beats/min83 ± 1785 ± 160.78
 Plasma creatinine, μmol/l121 ± 44111 ± 220.54
 Estimated GFR, ml/min56 ± 2262 ± 150.53
 BNP, pmol/l158 ± 151101 ± 730.35
 RAP, mm Hg7 ± 68 ± 50.61
 Mean PAP, mm Hg32 ± 1134 ± 80.57
 PCWP, mm Hg22 ± 926 ± 70.39
 Cardiac output, l/min4.9 ± 1.83.7 ± 0.80.08
 Cardiac index, l/min/m22.6 ± 0.91.8 ± 0.40.03

Values are mean ± SD, n, or %.

PAP = pulmonary artery pressure; PCWP = pulmonary capillary wedge pressure; RAP = right atrial pressure; other abbreviations as in Table 1.