Table 6

Incidence of CMV Events by Subgroup

Everolimus 1.5 mg
(n = 279)
MMF
(n = 268)
p Value
CMV infection
Laboratory evidence of CMV23 (8.2)55 (20.5)<0.001
CMV syndrome4 (1.4)18 (6.7)0.018
CMV disease5 (1.8)10 (3.7)0.196
CMV mismatch
D+/R+8/96 (8.3)20/84 (23.8)0.006
D+/R-9/59 (15.3)18/49 (36.7)0.014
Induction therapy
Basiliximab9/101 (8.9)17/97 (17.5)0.092
Thymoglobulin10/86 (11.6)21/83 (25.3)0.028
No induction4/91 (4.4)17/88 (19.3)0.002

Values are n (%) or n/N (%).

D = donor; MMF = mycophenolate mofetil; R = recipient.

  • Cytomegalovirus (CMV) syndrome was defined as fever lasting 2 days, neutropenia, leucopenia, or viral syndrome.

  • CMV disease was defined as organ involvement. Bold values indicate p<0.05.