Table 3

Variables Associated With Heart Failure Hospitalization Rates (Rate Ratio, 95% CI, and p Value) in the Multivariate Negative Binomial Regression Model

Rate Ratio95% CIp Value
Rosuvastatin versus placebo0.8150.72–0.920.001
Age1.0070.94–1.080.834
Female1.0830.93–1.270.316
NYHA class (compared to class II)
 III1.5151.32–1.74<0.001
 IV2.1461.35–3.400.001
Ejection fraction0.8030.75–0.86<0.001
Systolic blood pressure0.8530.80–0.91<0.001
Heart rate1.2681.19–1.35<0.001
Medical history
 Angina pectoris1.2911.12–1.49<0.001
 Diabetes mellitus1.5531.36–1.78<0.001
 Atrial fibrillation1.3501.19–1.54<0.001
 Pacemaker implanted1.3211.10–1.590.003
Laboratory measurements
 LDL cholesterol0.8820.83–0.94<0.001
 Serum creatinine1.2131.14–1.29<0.001
 NT-pro-BNP1.4041.33–1.48<0.001

CI = confidence interval; LDL = low-density lipoprotein; NT-pro-BNP = N-terminal pro-B type natriuretic peptide; NYHA = New York Heart Association.

  • Rate ratio is per 1-SD increase.