Focus Issue: Heart Failure Etiology and Outcomes - Clinical Research
Outcomes and Effect of Treatment According to Etiology in HFrEF
An Analysis of PARADIGM-HF
Craig Balmforth, Joanne Simpson, Li Shen, Pardeep S. Jhund, Martin Lefkowitz, Adel R. Rizkala, Jean L. Rouleau, Victor Shi, Scott D. Solomon, Karl Swedberg, Michael R. Zile, Milton Packer and John J.V. McMurray
Effect of Sacubitril/Valsartan According to Etiology of Heart Failure
Effect of randomized therapy with sacubitril/valsartan (sac/val) or enalapril on the primary composite outcome (A), or cardiovascular mortality (B) according to etiology (ischemic, idiopathic, hypertensive, and other). There was no significant treatment by etiology interaction. CI = confidence interval; HR = hazard ratio.