|First Author (Ref. #)||Findings||New in Current Analysis|
|Brouwers et al. (18)||Higher BMI was associated with overall HF without differences among HF subtypes among PREVEND participants.||Addition of other cohorts including FHS, CHS, and MESA for a more comprehensive analysis.|
|Eaton et al. (7)||Higher BMI was associated with incident HFpEF but not HFrEF among post-menopausal women participants of the WHI.||Inclusion of both men and women, and direct comparison of sex-specific effects and differences.|
|Ho et al. (15)||Higher BMI was associated with incident HFpEF and HFrEF among 28,820 participants from CHS, FHS, and PREVEND, with borderline difference among subtypes (p for equality 0.05).||Addition of MESA cohort for a more comprehensive analysis across 4 cohorts, specific investigation of obesity-related traits previously not analyzed, including waist circumference, insulin resistance, and dyslipidemia.|
|Ingelsson et al. (23)||Among ULSAM participants, BMI, insulin resistance, and waist circumference independently predicted incident overall HF.||Specific evaluation of insulin resistance and BMI and their associations with HF subtypes (HFpEF vs. HFrEF) with direct comparisons of effect sizes.|
|Vardeny et al. (25)||Among ARIC participants, insulin resistance and higher BMI were associated with increased risk of overall HF.||Specific evaluation of insulin resistance and BMI and their associations with HF subtypes (HFpEF vs. HFrEF) with direct comparisons of effect sizes.|
HF = heart failure; other abbreviations as in Table 2.