Phrenic Nerve Stimulation for the Treatment of Central Sleep Apnea
William T. Abraham, Dariusz Jagielski, Olaf Oldenburg, Ralph Augostini, Steven Krueger, Adam Kolodziej, Klaus-Jürgen Gutleben, Rami Khayat, Andrew Merliss, Manya R. Harsch, Richard G. Holcomb, Shahrokh Javaheri, Piotr Ponikowski and on behalf of the remedē Pilot Study Investigators
Graphical Representation of Phrenic Nerve Stimulation Delivered by the remedē System During Sleep
Phrenic neurostimulation stimulates the diaphragm during sleep to stabilize gas exchange and maintain normal breathing. Typical pulse stimulation characteristics are 0.1 to 10 mA for 60 to 300 μs at 20 to 40 Hz.